Intraoperative use of tranexamic acid in the control of bleeding in long bong fracture surgeries: a meta-analysis

<p class="abstract">Tranexamic acid (TXA) has been used successfully in the practice of orthopedics to reduce perioperative blood loss, particularly total hip and knee arthroplasty spine surgery. The use TXA shown potential transfusion rates volumes, hemoglobin change hospital-related costs at various degrees. This review aimed evaluate clinical results intraoperative long bone fracture surgeries. Relevant electronic articles were reviewed through a systematic search selection process, resulting five randomized control trials with 295 participants. These studies compared primary outcome this meta-analysis, which was loss. Four included post-operative levels as their outcomes. Furthermore, two drop levels, while three events. Results showed significant difference terms loss when administration placebo surgeries mean -76.94 [-106.62, -47.26] (95% CI) (p≤0.00001). There no (p=0.27) 0.31 [-0.24, 0.86] CI). No also between groups (p=0.29) -0.34 [-0.97, 0.29] meta-analysis that given during can effectively risk events or avoid events.</p>